2021 NSDUH Methodology Resources
Methodological Summary and Definitions (MSD) Report
Use this summary report to properly interpret 2021 NSDUH estimates of substance use and mental health issues. The report accompanies the annual detailed tables and covers overall methodology, key definitions for measures and terms used in 2021 NSDUH reports and tables, and selected analyses of the measures and how they should be interpreted.
The report is organized into six chapters:
- Introduction.
- Description of the survey, including information about the sample design, data collection procedures, and key aspects of data processing such as development of the analysis weights. The report also includes methodological changes and related issues in the 2021 NSDUH due to COVID-19.
- Technical details on the statistical methods and measurement, such as suppression criteria for unreliable estimates, statistical testing procedures, issues around selected substance use and mental health measures, and the impact of methodological changes on response rates.
- Special topics related to prescription psychotherapeutic drugs.
- A comparison between NSDUH and other sources of data on substance use and mental health issues, including data sources for populations outside the NSDUH target population.
- A more in-depth view of special methodological issues for the 2021 NSDUH, including the results of special analyses that led SAMHSA to not compare estimates from 2021 to estimates from previous years.
An appendix covers key definitions used in NSDUH reports and tables.
Methodological Resource Book (MRB) Collection
Use this collection to provide context for estimates from the National Survey on Drug Use and Health (NSDUH). This collection includes materials used to conduct the survey, reports on how the survey was conducted, and reports on how the data were processed. The Statistical Inference Report details how the data were analyzed for reports and tables, which may be useful for data users looking to do their own analysis.
New items are added to the collection as they become available, so resources published in a previous MRB may not yet be available for 2021. However, there are generally few changes from year to year, and a report from a previous year may have the information you are looking for.
Last Updated: 2/13/2025