This publication presents national estimates of drug-related visits to hospital emergency departments (EDs) for 2011, based on data from the Drug Abuse Warning Network (DAWN). Also presented are comparisons of 2011 estimates with those for 2004, 2009 and 2010. Chapter topics include overall drug misuse and abuse, illicit drugs, alcohol (drugs and alcohol taken together, underage drinking), nonmedical use of pharmaceuticals, drug-related suicide attempts, seeking detox services, adverse reactions to pharmaceuticals and accidental ingestion of drugs.