Evidence-Based Practices Resource Center

SAMHSA is committed to improving prevention, treatment, and recovery support services for mental and substance use disorders.

This new Evidence-Based Practices Resource Center aims to provide communities, clinicians, policy-makers and others in the field with the information and tools they need to incorporate evidence-based practices into their communities or clinical settings. The Resource Center contains a collection of scientifically-based resources for a broad range of audiences, including Treatment Improvement Protocols, toolkits, resource guides, clinical practice guidelines, and other science-based resources.

Learn more about the Evidence-Based Practices Resource Center.

View additional emerging practices.

Featured Resources

Principles of Community-Based Behavioral Health Services for Criminal Justice-Involved Individuals

This guide provides information and practices that behavioral health providers can implement in their daily practice with patients or clients who are involved in the criminal justice system.

Civil Commitment and the Mental Health Care Continuum

This document provides guidance to assist state policymakers and practitioners in reforming, implementing, and appropriately targeting commitment law and practice.

All Resources

+Filters

The objective of this systematic review is to assess safety, efficacy, and effectiveness of opioids taken long-term for CNCP.

Topic Area:
Opioid-Specific Resources
Populations:
Adults, Children and Youth
Target Audience:
Care Providers, Clinicians, Educators, Patients, Policymakers
Substances:
Opioids
Conditions:
Pain Management

The purpose of this systematic review is to determine optimal doses, routes of administration, and dosing strategies of naloxone for suspected opioid overdose in out-of-hospital settings, and whether transport to a hospital following successful opioid overdose reversal with naloxone is necessary.

Topic Area:
Opioid-Specific Resources
Populations:
Adults, Children and Youth
Target Audience:
Care Providers, Clinicians, Community Organizations, Educators, Family and Caregivers, Patients, Policymakers, Prevention Professionals
Substances:
Opioids
Conditions:
Opioid Overdose Prevention

Technical brief describing and comparing four core management strategies to reduce psychiatric readmissions--length of stay for inpatient care, transition support services i.e., care provided as the individual moves to outpatient care, short-term alternatives to psychiatric rehospitalization i.e., short-term outpatient care provided in place of psychiatric rehospitalization for those not at significant risk of harm to self or others, and long-term approaches for reducing psychiatric rehospitalization--for patients at high risk of psychiatric readmission.

Topic Area:
Serious Mental Illness and other Mental Health
Populations:
Adults
Target Audience:
Care Providers, Clinicians, Policymakers, Program Planners and Administrators
Conditions:
Inpatient Treatment, Serious Mental Illness

Systematic evidence review assessing effectiveness and safety of medical interventions for children with autism spectrum disorder.

Topic Area:
Serious Mental Illness and other Mental Health
Populations:
Target Audience:

This manual provides guidance on the use of medication-assisted treatment for alcohol use misuse. It summarizes approved medications, screening and assessment, treatment planning, and patient monitoring.

Topic Area:
Substance Use Treatment & Recovery
Populations:
Adults
Target Audience:
Care Providers, Clinicians, Community Organizations, Patients, Policymakers, Program Planners and Administrators
Substances:
Alcohol
Conditions:
Substance Use Treatment

This environmental scan describes the significant challenges and barriers that may limit access to MAT services in rural primary care settings, including those related to workforce, stigma, logistics, financing, and policy. The report also highlights essential characteristics of effective MAT practices and identifies three innovative models of care that may help overcome challenges to implementing MAT services in rural primary care settings.

Topic Area:
Opioid-Specific Resources
Populations:
Adults
Target Audience:
Care Providers, Clinicians, Community Organizations, Educators, Family and Caregivers, Patients, Policymakers, Prevention Professionals, Program Planners and Administrators, Public
Substances:
Opioids
Conditions:
Opioid Use Disorder Treatment, Substance Use Recovery, Substance Use Treatment

This document includes nearly 250 tools and resources available to providers, patients, and communities to help implement MAT in rural primary care settings. These tools have been categorized by topic and address the full spectrum of needs for patients.

Topic Area:
Opioid-Specific Resources
Populations:
Adults
Target Audience:
Care Providers, Clinicians, Community Organizations, Educators, Family and Caregivers, Patients, Policymakers, Prevention Professionals, Public
Substances:
Opioids
Conditions:
Opioid Use Disorder Treatment, Substance Use Recovery, Substance Use Treatment

This Technical Brief describes promising and innovative medication-assisted treatment (MAT) models of care in primary care settings, describe barriers to MAT implementation, summarize the evidence available on MAT models of care in primary care settings, identifies gaps in the evidence base, and guides future research.

Topic Area:
Opioid-Specific Resources
Populations:
Adults, Children and Youth
Target Audience:
Care Providers, Clinicians, Community Organizations, Educators, Patients, Policymakers, Prevention Professionals, Program Planners and Administrators
Substances:
Opioids
Conditions:
Opioid Use Disorder Treatment, Substance Use Treatment

This guide is for physicians using medication-assisted treatment for patients with opioid use disorder.

Topic Area:
Opioid-Specific Resources
Populations:
Adults, Children and Youth
Target Audience:
Care Providers, Clinicians, Policymakers
Substances:
Opioids
Conditions:
Opioid Use Disorder Treatment, Substance Use Treatment

This brief discusses effective prevention and treatment strategies for opioid misuse and addiction.

Topic Area:
Opioid-Specific Resources, Substance Use Treatment & Recovery
Populations:
Adults, Children and Youth
Target Audience:
Care Providers, Clinicians, Community Organizations, Educators, Family and Caregivers, Patients, Policymakers, Prevention Professionals, Public
Substances:
Opioids
Conditions:
Opioid Overdose Prevention, Opioid Use Disorder Treatment, Substance Use Prevention, Substance Use Treatment

This kit equips treatment teams at mental health agencies with guidance on incorporating the latest scientific evidence with patient input to help them make decisions about medication management.

Topic Area:
Serious Mental Illness and other Mental Health
Populations:
Adults
Target Audience:
Care Providers, Clinicians, Policymakers, Prevention Professionals, Program Planners and Administrators
Conditions:
Serious Mental Illness

The objectives of this study are to review published international monitoring guidelines, establish goals for metabolic monitoring, and make recommendations for practice for patients treated with antipsychotic medications.

Topic Area:
Serious Mental Illness and other Mental Health
Populations:
Adults
Target Audience:
Care Providers, Clinicians, Family and Caregivers, Patients, Program Planners and Administrators, Public
Conditions:
Serious Mental Illness

NAMI Family-to-Family is a free, 12-session educational program for family, significant others and friends of people living with mental illness. It is a designated evidenced-based program. Research shows that the program significantly improves the coping and problem-solving abilities of the people closest to an individual living with a mental health condition.

Topic Area:
Serious Mental Illness and other Mental Health
Populations:
Adults, Children and Youth
Target Audience:
Care Providers, Clinicians, Family and Caregivers, Patients, Policymakers, Program Planners and Administrators, Public
Conditions:
Serious Mental Illness

NASMHPD works with states, federal partners, and stakeholders to promote wellness, recovery, and resiliency for individuals with mental health conditions or co-occurring mental health and substance related disorders

Topic Area:
Serious Mental Illness and other Mental Health
Populations:
Adults
Target Audience:
Care Providers, Clinicians, Community Organizations, Educators, Family and Caregivers, Patients, Policymakers, Prevention Professionals, Program Planners and Administrators, Public
Conditions:
Serious Mental Illness

This review updates information about the clinical presentation of infants exposed to intrauterine drugs and the therapeutic options for treatment of withdrawal and is expanded to include evidence-based approaches to the management of the hospitalized infant who requires weaning from analgesics or sedatives.

Topic Area:
Substance Use Treatment & Recovery
Populations:
Adults, Children and Youth
Target Audience:
Care Providers, Clinicians, Policymakers, Program Planners and Administrators
Conditions:
Substance Use Treatment

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Last Updated: 04/14/2019