Evidence-Based Practices Resource Center

SAMHSA is committed to improving prevention, treatment, and recovery support services for mental and substance use disorders.

This new Evidence-Based Practices Resource Center aims to provide communities, clinicians, policy-makers and others in the field with the information and tools they need to incorporate evidence-based practices into their communities or clinical settings. The Resource Center contains a collection of scientifically-based resources for a broad range of audiences, including Treatment Improvement Protocols, toolkits, resource guides, clinical practice guidelines, and other science-based resources.

Learn more about the Evidence-Based Practices Resource Center.

View additional emerging practices.

Featured Resources

Principles of Community-Based Behavioral Health Services for Criminal Justice-Involved Individuals

This guide provides information and practices that behavioral health providers can implement in their daily practice with patients or clients who are involved in the criminal justice system.

Civil Commitment and the Mental Health Care Continuum

This document provides guidance to assist state policymakers and practitioners in reforming, implementing, and appropriately targeting commitment law and practice.

All Resources

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CollegeAIM—the College Alcohol Intervention Matrix—is a new resource to help schools address harmful and underage student drinking.

Topic Area:
SU Prevention, SU Treatment & Recovery
Populations:
Adults
Target Audience:
Community Organizations, Educators, Policymakers, Prevention Professionals, Program Planners and Administrators
Substances:
Alcohol
Conditions:
Substance Use Prevention, Substance Use Treatment

This systematic literature review addresses questions about the comparative effectiveness of smoking cessation treatments for patients with depression

Topic Area:
Serious Mental Illness and other Mental Health
Populations:
Adults
Target Audience:
Care Providers, Clinicians, Family and Caregivers, Patients, Policymakers, Program Planners and Administrators, Public
Substances:
Tobacco
Conditions:
Depression, Serious Mental Illness, Substance Use Treatment

This review compares early intervention services (EIS) with treatment as usual (TAU) for early-phase psychosis.

Topic Area:
Serious Mental Illness and other Mental Health
Populations:
Adults
Target Audience:
Prevention Professionals
Conditions:
Schizophrenia, Serious Mental Illness, Severe Emotional Disturbance

This manual offers guidance on improving services for people living with serious mental illness or emotional health issues during a mental health crises. It defines values, principles, and infrastructure to support appropriate responses to crises in diverse situations.

Topic Area:
Serious Mental Illness and other Mental Health
Populations:
Adults
Target Audience:
Care Providers, Clinicians, Community Organizations, Policymakers, Prevention Professionals, Program Planners and Administrators
Conditions:
Serious Mental Illness

This report presents the key principles and core expectations of the State Epidemiological Outcomes Workgroups to help inform prevention efforts.

Topic Area:
Substance Use Prevention
Populations:
Adults, Children and Youth
Target Audience:
Care Providers, Clinicians, Community Organizations, Educators, Family and Caregivers, Patients, Policymakers, Prevention Professionals, Program Planners and Administrators, Public
Conditions:
Substance Use Prevention

This handbook provides guidance on using the web-based, multimedia tool Decisions in Recovery: Medications for Opioid Addiction.

Topic Area:
Opioid-Specific Resources
Populations:
Adults, Children and Youth
Target Audience:
Care Providers, Clinicians, Community Organizations, Educators, Family and Caregivers, Patients, Policymakers, Public
Substances:
Opioids
Conditions:
Opioid Use Disorder Treatment, Substance Use Recovery, Substance Use Treatment

Systematic evidence review describing and reviewing the effectiveness of interventions that address disparities among adult patients with serious mental illness.

Topic Area:
Serious Mental Illness and other Mental Health
Populations:
Adults
Target Audience:
Care Providers, Clinicians, Family and Caregivers, Patients, Policymakers, Program Planners and Administrators, Public
Conditions:
Serious Mental Illness

Federal and National Resources compilation including information about preventing substance use. Includes organizations, programs, and websites, etc.

Topic Area:
Substance Use Prevention
Populations:
Adults, Children and Youth
Target Audience:
Community Organizations, Educators, Policymakers, Prevention Professionals, Program Planners and Administrators
Conditions:
Substance Use Prevention

This toolkit offers evidence-based practices to help public officials develop family psychoeducation-based mental health programs.

Topic Area:
Serious Mental Illness and other Mental Health
Populations:
Adults, Children and Youth
Target Audience:
Care Providers, Clinicians, Community Organizations, Educators, Family and Caregivers, Patients, Policymakers, Prevention Professionals, Program Planners and Administrators, Public
Conditions:
Serious Mental Illness

This manual provides guidelines for the operation of opioid treatment programs (OTPs). It covers patient assessment, treatment planning, and recovery care.

Topic Area:
Opioid-Specific Resources
Populations:
Adults
Target Audience:
Care Providers, Clinicians, Policymakers, Program Planners and Administrators
Substances:
Opioids
Conditions:
Opioid Use Disorder Treatment, Substance Use Recovery, Substance Use Treatment

Systematic evidence review assessing the effectiveness and harms of first- and second-generation antipsychotics FGAs and SGAs used for treating children, adolescents, and young adults.

Topic Area:
Serious Mental Illness and other Mental Health
Populations:
Children and Youth
Target Audience:
Care Providers, Clinicians, Family and Caregivers, Patients, Policymakers, Program Planners and Administrators, Public
Conditions:
Severe Emotional Disturbance

This manual helps communities plan and deliver substance use prevention strategies.

Topic Area:
Substance Use Prevention
Populations:
Adults, Children and Youth
Target Audience:
Community Organizations, Educators, Policymakers, Prevention Professionals, Program Planners and Administrators
Conditions:
Substance Use Prevention

This guide offers best practices for treating women living with substance use disorders in co-ed treatment and recovery settings.

Topic Area:
Substance Use Treatment & Recovery
Populations:
Women
Target Audience:
Care Providers, Clinicians, Community Organizations, Educators, Family and Caregivers, Patients, Policymakers, Program Planners and Administrators, Public
Conditions:
Substance Use Recovery, Substance Use Treatment

This Guidance document gives a “bird’s eye view” of strategies to support best practice prescribing of antipsychotics for youth and summarizes the available evidence and principles to support these strategies.

Topic Area:
Serious Mental Illness and other Mental Health
Populations:
Children and Youth
Target Audience:
Care Providers, Clinicians, Family and Caregivers, Patients, Public
Substances:
Prescription Drugs
Conditions:
Depression, Schizophrenia, Serious Mental Illness, Severe Emotional Disturbance, Suicide

An information series that provides clinicians with information related to alcohol.

Topic Area:
Substance Use Treatment & Recovery
Populations:
Adults
Target Audience:
Care Providers, Clinicians, Community Organizations, Patients, Policymakers, Program Planners and Administrators
Substances:
Alcohol
Conditions:
Substance Use Treatment

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Last Updated: 04/14/2019