Evidence-Based Practices Resource Center

SAMHSA is committed to improving prevention, treatment, and recovery support services for mental and substance use disorders.

This new Evidence-Based Practices Resource Center aims to provide communities, clinicians, policy-makers and others in the field with the information and tools they need to incorporate evidence-based practices into their communities or clinical settings. The Resource Center contains a collection of scientifically-based resources for a broad range of audiences, including Treatment Improvement Protocols, toolkits, resource guides, clinical practice guidelines, and other science-based resources.

Learn more about the Evidence-Based Practices Resource Center.

View additional emerging practices.

Featured Resources

Principles of Community-Based Behavioral Health Services for Criminal Justice-Involved Individuals

This guide provides information and practices that behavioral health providers can implement in their daily practice with patients or clients who are involved in the criminal justice system.

Civil Commitment and the Mental Health Care Continuum

This document provides guidance to assist state policymakers and practitioners in reforming, implementing, and appropriately targeting commitment law and practice.

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This tool guides clinicians through a series of questions to identify risky substance use in their adult patients. The accompanying resources assist clinicians in providing patient feedback and arranging for specialty care, where necessary, using the 5 As of intervention.

Topic Area:
Substance Use Prevention
Populations:
Adults
Target Audience:
Care Providers, Clinicians, Policymakers, Program Planners and Administrators
Substances:
Alcohol, Illicit Drugs, Prescription Drugs, Tobacco
Conditions:
Substance Use Prevention

The objective of this review is to compare the benefits and harms of second-generation antidepressants (SGAs), psychological, complementary and alternative medicine, and exercise treatment options as first-step interventions for adult outpatients with acute-phase major depressive disorder (MDD), and as second-step interventions for patients with MDD who did not achieve remission after a first treatment attempt with SGAs.

Topic Area:
Serious Mental Illness and other Mental Health
Populations:
Adults
Target Audience:
Care Providers, Clinicians, Family and Caregivers, Patients, Policymakers, Program Planners and Administrators, Public
Conditions:
Depression, Serious Mental Illness

This document provides facts about treatment from The American Society of Addiction Medecine (ASAM) - the leading medical society for addiction treatment.

Topic Area:
Opioid-Specific Resources
Populations:
Adults, Children and Youth, People in the Criminal Justice System, Women
Target Audience:
Clinicians
Substances:
Opioids
Conditions:
Opioid Use Disorder Treatment, Pain Management, Substance Use Disorders, Substance Use Treatment

This study describes approaches for transitioning from opioid agonists to detoxification followed by treatment with the opioid antagonist naltrexone as a treatment option for patients.

Topic Area:
Opioid-Specific Resources
Populations:
Adults, Children and Youth
Target Audience:
Care Providers, Clinicians, Policymakers
Substances:
Opioids
Conditions:
Opioid Use Disorder Treatment, Substance Use Treatment

This toolkit offers strategies to health care providers, communities, and local governments for developing practices and policies to help prevent opioid-related overdoses and deaths.

Topic Area:
Opioid-Specific Resources
Populations:
Adults, Children and Youth
Target Audience:
Care Providers, Clinicians, Community Organizations, Educators, Family and Caregivers, Patients, Policymakers, Prevention Professionals, Public
Substances:
Opioids
Conditions:
Opioid Overdose Prevention, Substance Use Prevention

Equipa a los proveedores de atención médica, las comunidades y los gobiernos locales con materiales para desarrollar prácticas y políticas para ayudar a prevenir las sobredosis y las muertes relacionadas con los opioides.

Topic Area:
Opioid-Specific Resources
Populations:
Adults, Children and Youth
Target Audience:
Care Providers, Clinicians, Community Organizations, Educators, Family and Caregivers, Patients, Policymakers, Prevention Professionals, Public
Substances:
Opioids
Conditions:
Opioid Overdose Prevention, Substance Use Prevention

Chronic pain is common, multidimensional, and individualized, and treatment can be challenging for healthcare providers as well as patients. In response to the critical need for consistent and current opioid prescribing guidelines, the CDC released the Guideline for Prescribing Opioids for Chronic Pain.

Topic Area:
Opioid-Specific Resources
Populations:
Adults, Children and Youth
Target Audience:
Care Providers, Clinicians, Community Organizations, Educators, Family and Caregivers, Patients, Policymakers, Prevention Professionals, Public
Substances:
Opioids
Conditions:
Pain Management

This toolkit outlines the essential components for supportive housing services and programs for people living with mental illness disorders.

Topic Area:
Serious Mental Illness and other Mental Health
Populations:
Adults
Target Audience:
Care Providers, Clinicians, Community Organizations, Policymakers, Program Planners and Administrators
Conditions:
Serious Mental Illness

This manual offers guidelines for medication-assisted treatment for people, particularly veterans, living with post-traumatic stress disorder and co-occurring opioid use disorders.

Topic Area:
Opioid-Specific Resources
Populations:
Adults, Children and Youth
Target Audience:
Care Providers, Clinicians, Policymakers
Substances:
Opioids
Conditions:
Co-Occurring Disorders, Opioid Use Disorder Treatment, Substance Use Treatment

Systematic evidence review and meta-analysis of the efficacy, comparative effectiveness, and harms of medications both FDA approved and others for adults with alcohol-use disorders, and to evaluate the evidence from primary care settings.

Topic Area:
Substance Use Treatment & Recovery
Populations:
Adults
Target Audience:
Care Providers, Clinicians, Community Organizations, Educators, Family and Caregivers, Patients, Policymakers, Prevention Professionals, Program Planners and Administrators, Public
Substances:
Alcohol
Conditions:
Substance Use Treatment

This In Brief edition summarizes sections of the guide and offers updated principles, new questions and answers, new program information, and expanded references about preventing drug abuse among children and adolescents.

Topic Area:
Substance Use Prevention
Populations:
Children and Youth
Target Audience:
Educators

The purpose of this guide is to help prevention practitioners use the results of prevention research to address drug abuse among children and adolescents in communities across the country.

Topic Area:
Substance Use Prevention
Populations:
Children and Youth
Target Audience:
Care Providers, Clinicians, Community Organizations, Educators, Family and Caregivers, Patients, Policymakers, Prevention Professionals, Program Planners and Administrators, Public
Conditions:
Substance Use Prevention

This technical package represents a select group of strategies based on the best available evidence to help communities and states sharpen their focus on prevention activities with the greatest potential to prevent suicide.

Topic Area:
Serious Mental Illness and other Mental Health
Populations:
Adults
Target Audience:
Care Providers, Clinicians, Policymakers, Prevention Professionals, Program Planners and Administrators
Conditions:
Serious Mental Illness, Suicide

SAMHSA/CSAP's comprehensive collection of relevant, practical, evidence-based approaches for preventing substance misuse.

Topic Area:
Substance Use Prevention
Populations:
Adults, Children and Youth
Target Audience:
Community Organizations, Educators, Policymakers, Prevention Professionals, Program Planners and Administrators
Conditions:
Substance Use Prevention

This chapter discusses the predictors of substance use initiation early in life and substance misuse throughout the lifespan, called risk factors, as well as factors that can mitigate those risks, called protective factors.

Topic Area:
Substance Use Prevention
Populations:
Adults, Children and Youth
Target Audience:
Care Providers, Clinicians, Community Organizations, Educators, Family and Caregivers, Patients, Policymakers, Prevention Professionals, Program Planners and Administrators, Public
Conditions:
Substance Use Prevention

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Last Updated: 04/14/2019