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Strategic Prevention Framework - Partnerships for Success (SPF-PFS) Grant Program


Short title: SPF-PFS

What is the Strategic Prevention Framework - Partnerships for Success (SPF-PFS) Program?

The SPF-PFS grant program is a foundational investment in substance use prevention in the U.S.

SPF-PFS focuses on: preventing substance use initiation and reducing the progression of substance use (and related problems) — by supporting the development and implementation of comprehensive, evidence-based prevention strategies — while also strengthening prevention capacity and infrastructure at the community and state levels.

SPF-PFS supports: a comprehensive prevention strategy, addressing locally identified priorities, using a data-driven process, enhancing protective factors, reducing risk factors, and building capacity to implement prevention strategies.

Awardees use the Strategic Prevention Framework (PDF | 3.3 MB) (also available in Spanish) to guide their prevention planning efforts. Studies show that adherence to the principles in the Framework increases the likelihood that prevention efforts will focus on the substance use problems impacting the community, produce anticipated outcomes, reduce harmful behaviors, and keep communities healthier and safer.

 Awards Details

Administered by: Center for Substance Abuse Prevention

Funding Mechanism: Grant

Number of Current Grantees: 294 active grants (FY 2019 - FY 2023)

Current Funding Information (FY 2024 Notice of Funding Opportunity):

  • Anticipated Total Available Funding: Up to $31 million
  • Anticipated Number of Awards: 12 states and 41 communities
  • Anticipated Award Amount: Up to $1,250,000 per year for state applicants; up to $375,000 per year for community, tribal, or territory applicants

Authorization: 42 USC 290bb-22: Priority substance use disorder prevention needs of regional and national significance

Year Established: 2012

Who does SPF-PFS serve?/Who is eligible?

Who does SPF-PFS serve?

High-risk underserved communities and at-risk sub-populations identified in National Survey on Drug Use and Health (NSDUH), Youth Risk Behavior Surveillance System (YRBSS), Behavioral Risk Factor Surveillance System (BRFSS), and Monitoring the Future (MTF).

Who is eligible to apply for SPF-PFS grants?

  • States, U.S. territories, Pacific Jurisdictions, and the District of Columbia
  • Communities, local governments, universities, colleges, tribes, and tribal organizations
Program Highlights

Program Highlights

As of 2023, SPF-PFS provides two distinct funding opportunities (one for states, and one for communities) ― to better address the needs and leverage the unique strengths of each.

From 2020 to 2023, SPF-PFS grantees implemented evidence-based programs and practices ― which served close to 40 million people through individual- and group-based activities (such as parenting education and school-based interventions) and reached even more people through population-based activities (such as social norming campaigns; social media; and strengthened enforcement of existing laws on access to alcohol, tobacco, and other age-restricted substances). The evidence-based interventions implemented by grantees include programs listed in registries of “what works” in prevention (such as LifeSkills Training, Communities That Care, and Guiding Good Choices).

These figures are based on grantee-reported data from activities generated in accordance with funding requirements for SPF-PFS. Individuals might have been reached by more than one intervention, and therefore might be counted multiple times.

How can I apply?

How can I apply?

For additional details about funding, current grantees, and their program visit the SAMHSA Grants Dashboard.

Related Resources

Other Resources

Last Updated
Last Updated: 06/18/2024
Last Updated