Applying for a New SAMHSA Grant

These resources will help you find and apply for funding opportunities.

These resources will help you find and apply for funding opportunities.

IMPORTANT: SAMHSA is transitioning to the National Institutes of Health (NIH)’s electronic Research Administration (eRA) grants system. Due to this transition, SAMHSA has made changes to the application registration, submission, and formatting requirements for all FOAs. All applicants must register with NIH’s eRA Commons in order to submit an application. Applicants must also register with the System for Award Management (SAM) and (see PART II: Section I-1 and Section II-1 for all registration requirements).

Due to the new registration and application requirements, it is strongly recommended that applicants start the registration process six (6) weeks in advance of the application due date.

SAMHSA and NIH held a webinar and online question and answer session to explain the new eRA application process and offer resources for support. The following webinar materials are available:


Only domestic public and private non-profit entities can apply for SAMHSA grants. Check for any additional eligibility requirements in the specific SAMHSA Funding Opportunity Announcements (FOA), or on, to see if you are eligible to apply for that grant.

Choose a Funding Opportunity

Search SAMHSA’s FOAs on the Grant Announcements page or on

To find a SAMHSA funding opportunity on, enter either the Funding Opportunity Number (SAMHSA’s FOA number) or the Catalog of Federal Domestic Assistance (CFDA) number. Both numbers are on the cover page of the FOA.

Each FOA includes specific instructions for completing an application.

Information on Electronic Submission

Visit the Submitting Your Application page for information about the four separate registration processes you must complete to submit a grant application to SAMHSA.


  • SAMHSA requires that applications be submitted electronically through
  • Successfully submitted applications through will then proceed to the NIH eRA Commons system and validations. Once your submitted application is successfully validated by the NIH eRA Commons system, it will be forwarded to SAMHSA as the receiving institution for further review.
  • SAMHSA will not accept or consider any applications sent by email or fax, or hand-carried without an approved waiver. Please see the “Waiver of Electronic Submission” section on the Submitting Your Application for further details.

Watch a Webcast on How to Register, Find, and Apply Applicant Training Video - Register, Find, and Apply will help you learn more about registering, searching, and applying for federal grant opportunities.

Last Updated: 04/22/2019