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Grants to Prevent Prescription Drug/Opioid Overdose-Related Deaths

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Short Title: PDO
Initial Announcement Back to the Grants Dashboard

Notice of Funding Opportunity (NOFO)

NOFO Number: SP-21-002

Posted on Wednesday, December 30, 2020

Application Due Date: Monday, March 01, 2021

Catalog of Federal Domestic Assistance (CFDA) Number: 93.243

Intergovernmental Review (E.O. 12372):

Public Health System Impact Statement (PHSIS) / Single State Agency Coordination:


The Substance Abuse and Mental Health Services Administration (SAMHSA), Center for Substance Abuse Treatment (CSAT), is accepting applications for fiscal year (FY) 2021 Grants to Prevent Prescription Drug/Opioid Overdose-Related Deaths (Short title: PDO). The purpose of this program is to reduce the number of prescription drug/opioid overdose-related deaths and adverse events among individuals 18 years of age and older by training first responders and other key community sectors on the prevention of prescription drug/opioid overdose-related deaths and implementing secondary prevention strategies, including the purchase and distribution of naloxone to first responders.


Eligible applicants are agencies within states, including the District of Columbia, U.S. territories, Pacific jurisdictions, and the Red Lake Band of the Chippewa, that manage the 20 percent prevention set-aside of the Substance Abuse Prevention and Treatment Block Grant (SABG) and have completed a comprehensive substance abuse prevention strategic plan.

Award Information

Funding Mechanism: Grant

Anticipated Total Available Funding: $11,397,000

Anticipated Number of Awards: 13 awards

Anticipated Award Amount: Up to $850,000 per year

Length of Project: Up to 5 years

Cost Sharing/Match Required?: No

Proposed budgets cannot exceed $850,000 in total costs (direct and indirect) in any year of the proposed project. Annual continuation awards will depend on the availability of funds, grantee progress in meeting project goals and objectives, timely submission of required data and reports, and compliance with all terms and conditions of award.)

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