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Strategic Prevention Framework – Partnerships for Success for Communities, Local Governments, Universities, Colleges, and Tribes/Tribal Organizations

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Short Title: SPF-PFS-Communities/Tribes
Initial Announcement Back to the Grants Dashboard

Notice of Funding Opportunity (NOFO)

NOFO Number: SP-23-004

Posted on Monday, April 03, 2023

Application Due Date: Monday, June 05, 2023

Catalog of Federal Domestic Assistance (CFDA) Number: 93.243

Intergovernmental Review (E.O. 12372): Applicants must comply with E.O. 12372 if their state(s) participates. Review process recommendations from the State Single Point of Contact (SPOC) are due no later than 60 days after application deadline.

Public Health System Impact Statement (PHSIS) / Single State Agency Coordination: Applicants must send the PHSIS to appropriate State and local health agencies by application deadline. Comments from Single State Agency are due no later than 60 days after application deadline.


The purpose of this program is to help reduce the onset and progression of substance misuse and its related problems by supporting the development and delivery of community-based substance misuse prevention and mental health promotion services. The program is intended to expand and strengthen the capacity of local community prevention providers to implement evidence-based prevention programs.

This NOFO will remain open for three fiscal years.

The following are the due dates for each FY:

  • FY 2023: Applications are due by June 5, 2023
  • FY 2024: Applications are due by June 5, 2024
  • FY 2025: Applications are due by June 5, 2025

Applications submitted by the due date will be reviewed and funding decisions will be made by the end of the FY.

Applicants that do not receive funding are eligible to apply for the following fiscal year.


Eligibility is limited to domestic public or private, non-profit entities, including community-based organizations, federally recognized tribes, tribal organizations, local governments, and institutions of higher education.

Award Information

Funding Mechanism: Grant

Anticipated Total Available Funding: Up to $16,500,000

Anticipated Number of Awards: 44

Anticipated Award Amount: Up to $375,000 per award

Length of Project: Up to five years

Cost Sharing/Match Required?: No

Proposed budgets cannot exceed $375,000 in total costs (direct and indirect) in any year of the proposed project. Annual continuation awards will depend on the availability of funds, grantee progress in meeting project goals and objectives, timely submission of required data and reports, and compliance with all terms and conditions of award.

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Last Updated

Last Updated: 06/12/2023