Strategic Prevention Framework - Partnerships for Success for Communities and Tribes

Short Title: SPF-PFS-Communities/Tribes
Initial Announcement Back to the Grants Dashboard

PLEASE NOTE: SAMHSA has received 60 complete, successfully submitted, and high-quality applications received via eRA. Given this threshold has been met, the submission portal is now closed, and no further applications will be considered.

Notice of Funding Opportunity (NOFO)

NOFO Number: SP-26-002

Posted on Grants.gov: Monday, June 15, 2026

Application Due Date: Friday, July 10, 2026

Catalog of Federal Domestic Assistance (CFDA) Number: 93.492

Intergovernmental Review (E.O. 12372): Applicants must comply with E.O. 12372 if their state(s) participates. Review process recommendations from the State Single Point of Contact (SPOC) are due no later than 60 days after application deadline.

Public Health System Impact Statement (PHSIS) / Single State Agency Coordination: Applicants must send the PHSIS to appropriate State and local health agencies by application deadline. Comments from Single State Agency are due no later than 60 days after application deadline.

Description

The purpose of this program is to: help prevent and reduce the initiation and progression of substance use and its related problems by supporting the development and delivery of community-based substance use prevention services that strengthen protective factors, reduce risk factors, build resilience, and promote well-being and expand and strengthen the capacity of prevention providers serving communities and tribes to implement evidence-based and evidence-informed prevention strategies.

IMPORTANT NOTE: SAMHSA will accept and review only the first 60 complete, successfully submitted, and high-quality applications received via eRA. Once this threshold is met, the submission portal will close, and no further applications will be considered.

Eligibility

Eligibility is statutorily limited to political subdivisions of States; Indian tribes or tribal organizations (as such terms are defined in section 5304 of title 25); health facilities or programs operated by or in accordance with a contract or award with the Indian Health Service; or other public or private non-profit entities, including faith-based organizations.

Award Information

Funding Mechanism: Grant

Anticipated Total Available Funding: $8,000,000

Anticipated Number of Awards: 13-32

Anticipated Award Amount: Up to $250,000-$600,000 per year per award

Length of Project: Up to 5 Years

Cost Sharing/Match Required?: No

Proposed budgets cannot exceed $250,000-$600,000 in total costs (direct and indirect) in any year of the proposed project. Annual continuation awards are contingent on the availability of funds, progress in meeting project goals and objectives, timely submission of required data and reports, compliance with all terms and conditions of award, and alignment with SAMHSA, HHS, and Trump Administration priorities.

Contact Information

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