Short Title:
PYO-TREAT
Initial Announcement
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Notice of Funding Opportunity (NOFO)
NOFO Number: TI-26-017
Posted on Grants.gov: Tuesday, June 16, 2026
Application Due Date: Thursday, July 16, 2026
Catalog of Federal Domestic Assistance (CFDA) Number: 93.490
Intergovernmental Review (E.O. 12372): Applicants must comply with E.O. 12372 if their state(s) participates. Review process recommendations from the State Single Point of Contact (SPOC) are due no later than 60 days after application deadline.
Public Health System Impact Statement (PHSIS) / Single State Agency Coordination: Applicants must send the PHSIS to appropriate State and local health agencies by application deadline. Comments from Single State Agency are due no later than 60 days after application deadline.
Description
The purpose of this program is to improve local awareness among youth and young adults of the risks associated with fentanyl and provide youth and young adults with opioid use disorder and other substance use disorder prevention, treatment and recovery support services.
Eligibility
Eligible applicants are statutorily limited (per 42 U.S.C. 290bb-7a).
Award Information
Funding Mechanism: Grant
Anticipated Total Available Funding: $2,700,000
Anticipated Number of Awards: 6
Anticipated Award Amount: $450,000
Length of Project: 3 years
Cost Sharing/Match Required?: No
Proposed budgets cannot exceed $450,000 in total costs (direct and indirect) in any year of the proposed project. Annual continuation awards are contingent on the availability of funds, progress in meeting project goals and objectives, timely submission of required data and reports, compliance with all terms and conditions of award, and alignment with SAMHSA, HHS, and Trump Administration priorities.
Contact Information
Program and Eligibility Questions
Arianna Douglas
Center of Substance Abuse Treatment
240-276-1600
PYOTREAT@samhsa.hhs.gov
Financial and Budget Questions
Office of Financial Resources
Division of Grants Management
240-276-1400
NOFOBudget.CSAT@samhsa.hhs.gov