Title

How to Apply for a SAMHSA Grant

Organization Registrations

To apply for SAMHSA funding, you must be registered in the following three systems:

  1. System for Award Management (SAM)
  2. Grants.gov
  3. eRA Commons

Start now! It can take six weeks or more to complete the registration process.

If your organization is not registered and you do not have an active eRA Commons PI account by the deadline, the application will not be accepted. No exceptions will be made.

More information on the registration process can be found in the Notice of Funding Opportunity (NOFO) Application Guide.

Choose a Notice of Funding Opportunity (NOFO)

Search for a NOFO on the SAMHSA Grants Dashboard. You can also search Grants.gov by the Notice of Funding Opportunity Number or the Assistance Listing number. Each NOFO includes specific information about the program requirements.

Eligibility

Specific eligibility requirements are found in the eligibility section of the NOFO posted on the Grants Dashboard and Grants.gov.

NOFO Application Guide

The Notice of Funding Opportunity (NOFO) Application Guide provides detailed instructions for preparing and submitting your SAMHSA grant application. This guide is referenced throughout the NOFO.

The Application Guide helps applicants to understand key parts of the application process, including the registration requirements, required attachments, and preparing your budget. In addition, there is valuable information about federal policies and regulations you must follow.

Additional Application Forms and Resources

If you are applying for a SAMHSA grant, you must download the application forms found on Grants.gov. You may require additional forms found on the SAMHSA website. Read the NOFO carefully to determine which forms you must include in your application. Applications that do not include all required forms will be screened out and will not be eligible for review.


Need Help?

SAMHSA periodically presents live training webinars for prospective applicants interested in applying to grant programs. Webinars provide information on how to submit applications to SAMHSA using NIH’s eRA System, including registration and application processes, requirements and validations, and the post-submission process. Get other Grants Training Materials.

Grants.gov Help

The Grants.gov video library includes information about registering, searching, and applying for federal grant opportunities. Note that Grants.gov is periodically inaccessible due to service maintenance and system enhancements. Check Grants.gov for the outage calendar.

Applicant Tutorial Video

This presentation provides guidance for registering and preparing your organization to successfully initiate and submit applications.

Last Updated: 05/27/2026