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How to Apply for a SAMHSA Grant


Information is provided on how to apply for a SAMHSA Notice of Funding Opportunity (NOFO).


Only domestic public and private non-profit entities can apply for SAMHSA grants. Every SAMHSA NOFO posted on the Grants Dashboard and will include additional eligibility requirements.


All applicants must register with, the System for Award Management (SAM), and NIH's eRA Commons to submit an application. The registration process takes up to six weeks. Applications will not be accepted if your organization is not registered and you do not have an active eRA Commons PI account by the deadline. No exceptions will be made.

Understand the Registration Requirements

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Choosing a Funding Opportunity (NOFO)

Search for a NOFO on the SAMHSA Grants Dashboard. You can also search by the Notice of Funding Opportunity Number or the Assistance Listing number/Catalog of Federal Domestic Assistance (CFDA) number. Both numbers are on the cover page of the NOFO. Each NOFO includes specific instructions for completing an application.

Writing an Application

As you prepare to write an application, it is critical to review the standard forms that must be submitted as well as guidance on funding restrictions and policies related to federal grants.

How do I write an application?

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Submitting and Tracking an Application

Applications must be submitted electronically through Successfully submitted applications through will proceed to the NIH eRA Commons system to be validated. Successfully validated applications through the NIH eRA Commons system will then be forwarded to SAMHSA for further review.

How do I submit an application?

How do I track my grant application?

Budget and Justification

Budget and Narrative

All applications must include a detailed budget and narrative that explains the federal and the non-federal expenditures.


need help

Need Help?

SAMHSA periodically presents live training webinars for prospective applicants interested in applying to grant programs. Webinars provide information on how to submit applications to SAMHSA using NIH’s eRA System, including registration and application processes, requirements and validations, and the post-submission process. Check the Grants Dashboard's "FAQ's and Webinars" column to find NOFOs with these additional resources. Get other Grants Training Materials. Help

The video library includes information about registering, searching, and applying for federal grant opportunities. Note that is periodically inaccessible due to service maintenance and system enhancements. Check for the outage calendar.

Applicant Tutorial Video

This presentation provides guidance for registering and preparing your organization to successfully initiate and submit applications.

Last Updated

Last Updated: 06/05/2023

Last Updated