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Grants

HHS has agreed to stay enforcement and application through September 10, 2025, of the following item: U.S. Department of Health and Human Services, “Personal Responsibility and Work Opportunity Reconciliation Act of 1996 (PRWORA); Interpretation of ‘Federal Public Benefit,’” 90 Fed. Reg. 31,232 (July 14, 2025) (“HHS PRWORA Notice”). This period will permit the agency to consider, as appropriate, whether to provide additional information about the HHS PRWORA Notice.

Starting October 1, 2025, all awards issued by SAMHSA will be subject to the applicable provisions of 2 CFR 200 and 2 CFR 300. These federal regulations establish uniform administrative requirements, cost principles, and audit standards for federal awards, including those specific to the U.S. Department of Health and Human Services.

We recommend that all recipients familiarize themselves with these regulations and the current executive orders to ensure compliance moving forward.

For more information, please visit ecfr.gov or contact your assigned Grants Management Specialist.

Throughout the U.S., SAMHSA funds organizations providing substance use and mental health services, research, technical assistance, and training to advance the behavioral health and to improve the lives of individuals living with mental and substance use disorders, and their families.

About SAMHSA Grants

Learn more about SAMHSA grant processes and oversight.

Grants Hero Image

SAMHSA announces grant funding opportunities through Notice of Funding Opportunities (NOFOS). Each NOFO contains all the information you need to apply for a grant.

Information is provided on how to apply for a SAMHSA Notice of Funding Opportunity (NOFO).

Do you have questions about grant announcements, issues with submitting your application, or technical questions about eRA Commons? Contact us.

In the post-award phase of the grant, the agency collaborates with the grant recipient (grantee) to ensure progress on SAMHSA supported programs while minimizing risks to Federal funds.

Updates

  • Federal financial assistance award recipients are a crucial part of safeguarding Federal funds and maintaining a secure cyber environment. Check out this Grants.gov blog post to learn more.
  • A significant change has been made to the registration process for the System for Award Management (SAM). Please refer to the FAQs on the SAM website.
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Last Updated: 09/08/2025