Publications and Research

Find SAMHSA publications and related resources about medication-assisted treatment (MAT).

SAMHSA Publications and Resources on Medication-Assisted Treatment (MAT)

The SAMHSA Center for Substance Abuse Treatment (CSAT) publishes Dear Colleague Letters, official SAMHSA guidance for physicians and other professionals on a variety of issues related to MAT.

SAMHSA’s Division of Pharmacologic Therapies (DPT) also makes available publications and resources about opioid overdose, naloxone, and about other medications used in MAT.

SAMHSA Publications on Buprenorphine

Other Government Publications on Buprenorphine

Journal Articles on Opioid Treatment

The January-February 2010 issue of The American Journal on Addictions contains peer-reviewed articles authored by DPT staff members. The articles underscore the clinical consequences of drug interactions between opioid therapies and other medications as well as with other misused substances.

Journal Articles on Buprenorphine








Use in Pregnancy


Other Resources

This list of MAT-related resources was developed by SAMHSA’s federal partners and partnering organizations:

Connect with federal agencies, patient groups, and other support organizations that provide educational and other resources for MAT professionals and patients. Learn more about medication and counseling treatment.

Last Updated: 09/09/2019