State Grant Programs

Grant programs available to states.

MAT-PDOA - The MAT-PDOA grant program helps states expand or enhance their treatment systems to improve access to evidence-based MAT services.

State Targeted Response to the Opioid Crisis Grants (Opioid-STR) - The Opioid-STR grant program helps states, territories and jurisdictions expand prevention, treatment and recovery support services for individuals with an opioid use disorder (OUD).


The misuse of prescription pain relievers containing opioids and the use of illicit drugs such as heroin is a serious and challenging public health concern. In 2010, prescription and illicit drug overdoses in the United States killed 38,329 people, with 30,006 of those deaths being unintentional. These numbers exceed deaths that year from traffic accidents, guns violence, or falls.

Goals of the MAT-PDOA Grant Program

MAT-PDOA is a three-year grant program to address the opioid misuse and addiction problem in this country.

MAT-PDOA provides funding to states to:

  • Enhance or expand their treatment service systems to increase access to MAT by building capacity
  • Provide MAT and recovery services that are accessible, effective, comprehensive, coordinated, and evidence-based

Target populations include people with opioid use disorders who are seeking or receiving MAT, with a particular focus on racial, ethnic, sexual, and gender-identity minority groups. Examples of some of these populations include pregnant and parenting women, people in the criminal justice system, veterans, and rural communities.

As a result of the program, SAMHSA expects to:

  • Increase the number of admissions for MAT
  • Increase the number of clients receiving integrated care and treatment
  • Decrease illicit opioid drug use at six-month follow-up
  • Decrease the use of prescription opioids in a non-prescribed manner at six-month follow-up

About MAT-PDOA Grantees

MAT-PDOA grantees are states with high rates of primary treatment admissions for heroin and opioids per capita. To learn more about the grantee states’ programs and activities to address their specific challenges, review the 2015 MAT-PDOA grantee profiles.

MAT-PDOA grantees follow evidence-based practices and provide an array of MAT services. These services include the use of FDA-approved medications in conjunction with counseling and behavioral therapies, integrated care, and peer and recovery support. Learn more about medication and counseling treatment.

In addition, these services are designed to:

  • Decrease the use of opioids and reduce the risk of overdose among the target populations within at least two high-risk communities in their state
  • Develop partnerships with local government and/or community-based organizations to address community needs

How to Apply

For future MAT-PDOA Funding Opportunity Announcement (FOA) or on and information on applying for a new SAMHSA grant.

Contact Us:

Kim Thierry English, M.ED, NCAC II, MAC, Public Health Advisor, CSAT,, 240.276.2907

State Targeted Response to the Opioid Crisis Grants (Opioid-STR)

Goals of the Opioid-STR Grant Program

Opioid-STR is a two-year grant program to address the opioid crisis by increasing access to treatment, reducing unmet treatment need, and reducing opioid overdose related deaths through the provision of prevention, treatment and recovery activities for opioid use disorder (OUD) (including prescription opioids as well as illicit drugs such as heroin). Grantees must use funding to supplement and not supplant existing opioid prevention, treatment, and recovery activities in their state.

Opioid-STR provides funding to states to:

  • Conduct needs assessments and strategic plans
  • Identify gaps and resources from which to build upon existing substance use disorder prevention and treatment activities
  • Implement and expand access to clinically appropriate evidence-based practices for treatment for opioid use disorders particularly the use of medication-assisted treatment and recovery support services
  • Advance substance misuse prevention in coordination with other federal efforts such as those funded by the Centers for Disease Control and Prevention (CDC).

The populations of focus were identified in the states’, territories’ and jurisdictions’ respective needs assessments and strategic plans including, but not limited to, persons who inject drugs, pregnant women and women with dependent children, persons re-entering communities from jails and prisons, and veterans of the armed services.

About Opioid-STR Grantees

Opioid-STR grants are awarded to states, territories and jurisdictions via formula based on unmet need for opioid use disorder treatment and drug poisoning deaths.

Learn more about the grantee states’ proposed programs and activities to address their specific challenges: TI-17-014: State Targeted Response to the Opioid Crisis Grants (Opioid STR) Individual Grant Awards (PDF | 366 KB).

The expenditure of Opioid STR grant funds is intended to supplement and not supplant existing opioid prevention activities, treatment and recovery support services in their respective states, territories and jurisdictions. SAMHSA’s discretionary grants are for substance abuse prevention and treatment programs of regional and national significance, and formula grants are for the prevention and treatment of substance abuse support community- and faith-based organizations that provide such services. The Opioid STR grantees are also encouraged to promote coordination of care with the Health Resources and Services Administration’s Community Health Centers which received FY 2016 Substance Abuse Expansion Awards and FY 2017 Access Increases for Mental Health and Substance Abuse Services (AIMS) Awards.

Opioid State Targeted Response Supplement (STR Supplement)

In FY 2018, SAMHSA announced the availability of supplements to bolster efforts already being made through the Opioid STR grant program. The purpose of this program is to expand and enhance prevention, treatment, and recovery support efforts in the states hardest hit by the nation’s opioid epidemic. Eligible applicants are Opioid STR grantees with the top ten highest rates of overdose deaths in 2015 according to data reported by the Centers for Disease Control and Prevention. The following are those ten states: KY, MA, NH, NM, OH, PA, RI, TN, UT, and WV. Learn more about the Funding Opportunity Announcement.

Opioid State Targeted Response (STR) Technical Assistance


In FY 2018, SAMHSA announced the availability of funds for STR TA

The purpose of this program is to identify local physicians, other clinicians, and other providers, for example, advance practice nurses, physician assistants, peers and other healthcare professionals with expertise in treatment and in recovery services for opioid use disorders (OUDs). Based on a state, territory, or tribal nation’s assessed need, these providers will serve as the primary providers of federally supported TA for the program’s successful implementation. The goal of this TA is to ensure the provision of evidence-based prevention, treatment, and recovery support programs/services across the Opioid STR program. Learn more about STR TA.

Contact Us:

Donna J. Hillman, MEd, Public Health Advisor, CSAT,, 240-276-1249
Tonia F. Gray, MPH, Public Health Advisor, CSAP,, 240-276-2492

Last Updated: 03/04/2019