Learn how SAMHSA’s Division of Pharmacologic Therapies (DPT) works to oversee medication-assisted treatment (MAT) for substance use disorders. The Division of Pharmacologic Therapies (DPT), part of the SAMHSA Center for Substance Abuse Treatment (CSAT), manages the day-to-day oversight activities necessary to implement federal regulations on the use of substance use disorder medications such as methadone and buprenorphine. These activities include supporting the accreditation and certification of more than 1,250 opioid treatment programs (OTPs) that collectively treat more than 300,000 patients each year. Learn more about SAMHSA’s certification of OTPs and oversight of OTP Accrediting Bodies. DPT also implements the Drug Addiction Treatment Act of 2000 (DATA 2000). This law expands the clinical context of medication-assisted treatment (MAT) by allowing qualified physicians to dispense or prescribe medications for the treatment of opioid addiction in settings other than OTPs and other facilities. Learn about the different medications used in MAT approved by the Food and Drug Administration (FDA) to treat substance use disorders. Learn more about the legislation, regulations, and guidelines that govern MAT.