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SAMHSA Announces Unprecedented $30 Million Harm Reduction Grant Funding Opportunity to Help Address the Nation’s Substance Use and Overdose Epidemic

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The Substance Abuse and Mental Health Services Administration (SAMHSA) is now accepting applications for the first-ever SAMHSA Harm Reduction grant program and expects to issue $30 million in grant awards. This funding, authorized by the American Rescue Plan, will help increase access to a range of community harm reduction services and support harm reduction service providers as they work to help prevent overdose deaths and reduce health risks often associated with drug use. SAMHSA will accept applications from State, local, Tribal, and territorial governments, Tribal organizations, non-profit community-based organizations, and primary and behavioral health organizations.

With overdose deaths exceeding 100,000 over a 12-month period for the first time, this funding opportunity will provide support to those working in their communities to reduce the harms of drug use. Providing funding and support for innovative harm reduction services is in line with the Biden-Harris Administration’s ongoing efforts to address the overdose epidemic, and is a key pillar for the first time in the multi-faceted Health and Human Services’ overdose prevention strategy announced in October. This funding allows organizations to expand their community-based overdose prevention programs in a variety of ways, including distributing overdose-reversal medications and fentanyl test strips, providing overdose education and counseling, and managing or expanding syringe services programs, which help control the spread of infectious diseases like HIV and hepatitis C.

“The reality is, evidence-based harm reduction services are out of reach for far too many people,” said National Drug Control Policy Director Dr. Rahul Gupta, who also announced a new model law to help states ensure access to safe, effective, and cost-saving syringe services programs. “Building on the Biden-Harris Administration’s efforts to expand evidence-based prevention, treatment and recovery support services, this historic funding will help make harm reduction services more accessible, so we can meet people where they are and save lives.”

“Too many Americans, more than 100,000 people over the last year, have lost their lives to drug overdose. Our new HHS Overdose Prevention Strategy is clear – harm reduction services are critical to keeping people who use drugs alive and as healthy as possible,” said Health and Human Services Secretary Xavier Becerra. “Americans deserve health services that address the full range of drug use and addiction issues, and this funding will help provide those services in the neighborhoods in which they live.”

“Innovative harm reduction services will help keep Americans alive,” said Miriam Delphin-Rittmon, Ph.D., the Assistant Secretary for Mental Health and Substance Use and the leader of SAMHSA. “Thanks to this American Rescue Plan funding, harm reduction service providers in historically under-resourced communities will receive long-awaited support to help stem the disproportionate number of overdose deaths and related health issues facing those communities.”

SAMHSA will distribute $10 million per year over the next three years. Grant recipients must use the funds to support harm reduction services. Harm reduction service providers will be asked to develop or expand evidence-based services that may include, but not be limited to: the provision of sterile syringes, safe sex kits, prevention education about synthetic opioids and other substances, overdose prevention kits including naloxone distribution, peer worker engagement, medical services, case management and referral to treatment. Warm handoffs that facilitate engagement in care and referrals to treatment for individuals seeking these support services are also critical components of this grant program. Harm reduction services will be trauma-informed and guided by harm reduction stakeholder groups and other community members.

For more information about Harm Reduction, click here. To apply to this grant funding opportunity, click here

People searching for treatment for substance use disorders can find options by visiting or by calling SAMHSA’s National Helpline, 1-800-662-HELP (4357).

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The Substance Abuse and Mental Health Services Administration (SAMHSA) is the agency within the U.S. Department of Health and Human Services (HHS) that leads public health efforts to advance the behavioral health of the nation. SAMHSA’s mission is to lead public health and service delivery efforts that promote mental health, prevent substance misuse, and provide treatments and supports to foster recovery while ensuring equitable access and better outcomes.

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