Suicidal behavior is a major public health problem in the United States. The suicide rate has steadily increased over the past 2 decades. This large-scale cohort comparison study found that SPI+ was associated with a reduction in suicidal behavior and increased treatment engagement among suicidal patients following ED discharge and may be a valuable clinical tool in health care settings.

This article features the three main replicated treatments for suicide: Dialectical Behavior Therapy, Cognitive Therapy for Suicide Prevention, and the Collaborative Assessment and Management of Suicidality.

The objective of this review is to compare the benefits and harms of second-generation antidepressants (SGAs), psychological, complementary and alternative medicine, and exercise treatment options as first-step interventions for adult outpatients with acute-phase major depressive disorder (MDD), and as second-step interventions for patients with MDD who did not achieve remission after a first treatment attempt with SGAs.

This systematic literature review addresses questions about the comparative effectiveness of smoking cessation treatments for patients with depression