This guide provides practical, evidence-based information that first responder agencies, their partners, and communities can use to implement or expand practices and programs for linking people to substance use services.

This Treatment Improvement Protocol (TIP) reviews the use of the three Food and Drug Administration (FDA)-approved medications used to treat OUD—methadone, naltrexone, and buprenorphine—and the other strategies and services needed to support recovery for people with OUD