This guide presents three evidence-based practices that engage and improve outcomes for individuals with concurrent substance use and concurrent substance use disorders.

This guide reviews interventions for people living with substance use and mental disorders who are at risk for or living with HIV. Selected interventions are in alignment with goals of the federal “Ending the HIV Epidemic: A Plan for America” (EHE) initiative.

This guide supports health care providers, systems, and communities seeking to prevent vaping. It describes relevant research findings, examines emerging and best practices, identifies knowledge gaps and implementation challenges, and offers useful resources.

This guide supports health care providers, systems, and communities seeking to treat stimulant use disorders. It describes relevant research findings, examines emerging and best practices, identifies knowledge gaps and implementation challenges, and offers useful resources.

This guide focuses on using medication-assisted treatment for opioid use disorder in jails and prisons and during the reentry process when justice-involved persons return to the community. It provides an overview of policies and evidence-based practices that reduce the risk of overdose and relapse.

The Rx Pain Medications, Know the Options, Get the Facts is a series of 13 fact sheets designed to increase awareness of the risks associated with prescription opioid use and misuse, as well as to educate patients who are prescribed opioids for pain about the risks and to provide resources on methods for alternative pain management.

This advisory summarizes data on the use of sublingual and transmucosal buprenorphine as part of medication-assisted treatment (MAT) for opioid use disorder.

This manual offers best practices to states, tribes, and local communities on collaborative treatment approaches for pregnant women living with opioid use disorders, and the risks and benefits associated with medication-assisted treatment (MAT).

This Technical Brief describes promising and innovative medication-assisted treatment (MAT) models of care in primary care settings, describe barriers to MAT implementation, summarize the evidence available on MAT models of care in primary care settings, identifies gaps in the evidence base, and guides future research.

This document provides facts about treatment from The American Society of Addiction Medicine (ASAM) - the leading medical society for addiction treatment.

This guide highlights the use of medication-assisted treatment (MAT) for opioid use disorder in drug courts.

This Clinical Guide provides comprehensive, national guidance for optimal management of pregnant and parenting women with opioid use disorder and their infants. The Clinical Guide helps healthcare professionals and patients determine the most clinically appropriate action for a particular situation and informs individualized treatment decisions.

This manual provides guidelines for the operation of opioid treatment programs (OTPs). It covers patient assessment, treatment planning, and recovery care.

This manual offers guidelines for medication-assisted treatment for people, particularly veterans, living with post-traumatic stress disorder and co-occurring opioid use disorders.

This Treatment Improvement Protocol (TIP) reviews the use of the three Food and Drug Administration (FDA)-approved medications used to treat OUD—methadone, naltrexone, and buprenorphine—and the other strategies and services needed to support recovery for people with OUD

This CDC document consists of evidence-based strategies to reduce overdose including naloxone distribution and medication-assisted therapy. It aims to assist community leaders, local and regional organizers, non-profit groups, law enforcement, public health, and members of the public in understanding and navigating effective strategies.

This Harm Reduction Coalition (HRC) manual outlines the process of developing an Overdose Prevention and Education Program, with or without a take-home naloxone component. Such a program may be integrated into existing services for people affected by substance abuse, including shelter and supportive housing agencies, treatment programs, parent and student groups, and communities at-large.

This toolkit provides correctional administrators and health care providers recommendations and tools for implementing medication-assisted treatment (MAT) in correctional settings. It provides examples from the field that can be widely applied and adapted for programs that serve justice-involved individuals.