This guide provides practical, evidence-based information that first responder agencies, their partners, and communities can use to implement or expand practices and programs for linking people to substance use services.

This advisory discusses the epidemiology of the mental health symptoms and conditions of Long COVID, provides evidence-based resources for the treatment of those conditions, and offers possible resources.

This advisory introduces readers to cannabidiol (CBD), how it is derived, and how it differs from delta-9 THC and other cannabinoids. The advisory focuses on the risks and harms of CBD, especially those sold over the counter. This advisory also clarifies common misconceptions about CBD, given its broad availability and marketing for several medical conditions despite limited evidence of efficacy.

This guide highlights strategies for behavioral health and housing providers to conduct outreach and engage with individuals experiencing homelessness, initiate use of behavioral health treatment as they wait to receive stable housing and retain them in their recovery efforts once housed.

Community engagement is often cited as a tool to improve the health of the community and its members. This guide will review evidence related to leveraging community engagement to support the implementation and scale-up of evidence-based programs and policies.

This guide reviews interventions for people living with substance use and mental disorders who are at risk for or living with HIV. Selected interventions are in alignment with goals of the federal “Ending the HIV Epidemic: A Plan for America” (EHE) initiative.

This guide supports health care providers, systems, and communities seeking to prevent vaping. It describes relevant research findings, examines emerging and best practices, identifies knowledge gaps and implementation challenges, and offers useful resources.

This guide supports health care providers, systems, and communities seeking to treat stimulant use disorders. It describes relevant research findings, examines emerging and best practices, identifies knowledge gaps and implementation challenges, and offers useful resources.

This guide supports health care providers, systems, and communities seeking to prevent marijuana use by pregnant women. It describes relevant research findings, examines emerging and best practices, identifies knowledge gaps and implementation challenges, and offers useful resources.

The goal of this guide is to review the literature on treating substance misuse and substance use disorders in the context of first-episode psychosis, distill the research into recommendations for practice, and provide examples of the ways that these recommendations can be implemented by first-episode psychosis treatment programs.

This guide examines a wide range of evidence-based practices for screening and assessment of people in the justice system who have co-occurring mental and substance use disorders.

The Rx Pain Medications, Know the Options, Get the Facts is a series of 13 fact sheets designed to increase awareness of the risks associated with prescription opioid use and misuse, as well as to educate patients who are prescribed opioids for pain about the risks and to provide resources on methods for alternative pain management.

This Clinical Guide provides comprehensive, national guidance for optimal management of pregnant and parenting women with opioid use disorder and their infants. The Clinical Guide helps healthcare professionals and patients determine the most clinically appropriate action for a particular situation and informs individualized treatment decisions.

This fact sheet offers young adults information on living with psychosis. It discusses causes of psychosis, and approaches to treatment.

This kit provides practice principles for supported employment, an approach to vocational rehabilitation for people living with serious mental illness.

This brief defines drug addiction and discusses treatment approaches for combating it.

This document provides state by state information on implementation of intensive care coordination using a wraparound approach for children and youth with complex mental and substance use disorders.

Zero Suicide operationalizes the core components necessary for health care systems to transform suicide care into seven elements. Within each element section, find a description of what each element is, why it is necessary to Zero Suicide implementation, a summary of supporting research, and key readings and tools. Use the navigation bar that appears at the top of each element page to jump between sections.

This document evaluates states’ use of best practices in preventing underage drinking, as required by the STOP Act.

This guide discusses the challenges in care transitions and the need for better care practices and care coordination from inpatient to outpatient behavioral health care, and presents feasible, evidence-based practices that health systems and providers can take to improve patient connection and safety during inpatient to outpatient transition, and provides recommendations specific to both inpatient and outpatient settings.

Effective Interventions offers capacity-building assistance resources for CDC-supported HIV prevention and treatment evidence-based interventions. This CDC website is organized according to the four pillars of the Ending the HIV Epidemic initiative (Diagnose, Treat, Prevent, Respond). It includes links to request classroom trainings and technical assistance to support implementation of these interventions if funding permits.

Developed by the Collaboration for Academic, Social, and Emotional Learning (CASEL), this guide offers an organizational framework for instilling social emotional learning (SEL) principles into education systems. SEL is the process through which children and adults develop the knowledge, attitudes, and skills to manage emotions, achieve positive goals, display empathy for others, build positive relationships, and make responsible decisions.

This fact sheet developed by CDC’s National Institute for Occupational Safety and Health (NIOSH) helps employers understand the risk of opioid overdose and allows them to decide if they should establish a workplace naloxone availability and use program.

This Harm Reduction Coalition (HRC) manual outlines the process of developing an Overdose Prevention and Education Program, with or without a take-home naloxone component. Such a program may be integrated into existing services for people affected by substance abuse, including shelter and supportive housing agencies, treatment programs, parent and student groups, and communities at-large.