This guide reviews interventions on treating substance misuse and substance use disorders (SUD) in youth with serious emotional disturbances (SED), distills the research into recommendations for practice, and provides examples of the ways that these recommendations can be implemented.

This guide reviews interventions for people living with substance use and mental disorders who are at risk for or living with HIV. Selected interventions are in alignment with goals of the federal “Ending the HIV Epidemic: A Plan for America” (EHE) initiative.

This guide supports health care providers, systems, and communities seeking to prevent marijuana use by pregnant women. It describes relevant research findings, examines emerging and best practices, identifies knowledge gaps and implementation challenges, and offers useful resources.

The goal of this guide is to review the literature on treating substance misuse and substance use disorders in the context of first-episode psychosis, distill the research into recommendations for practice, and provide examples of the ways that these recommendations can be implemented by first-episode psychosis treatment programs.

This guide examines a wide range of evidence-based practices for screening and assessment of people in the justice system who have co-occurring mental and substance use disorders.

The purpose of this systematic review is to evaluate treatments for adults with schizophrenia.

Systematic evidence review assessing the effectiveness and harms of first- and second-generation antipsychotics FGAs and SGAs used for treating children, adolescents, and young adults.

This TIP is intended to help a wide range of providers become familiar with the various issues surrounding clients with both substance use and human immunodeficiency virus (HIV) and to foster a better understanding of the roles of other providers.

This document provides state by state information on implementation of intensive care coordination using a wraparound approach for children and youth with complex mental and substance use disorders.

Effective Interventions offers capacity-building assistance resources for CDC-supported HIV prevention and treatment evidence-based interventions. This CDC website is organized according to the four pillars of the Ending the HIV Epidemic initiative (Diagnose, Treat, Prevent, Respond). It includes links to request classroom trainings and technical assistance to support implementation of these interventions if funding permits.