Systematic evidence review and meta-analysis of the efficacy, comparative effectiveness, and harms of medications both FDA approved and others for adults with alcohol-use disorders, and to evaluate the evidence from primary care settings.

This is a summary of a systematic review evaluating the evidence regarding the efficacy, comparative effectiveness, and adverse effects of medications in adults with Alcohol Use Disorder.

Systematic evidence review assessing the effectiveness and harms of first- and second-generation antipsychotics FGAs and SGAs used for treating children, adolescents, and young adults.

The purpose of this systematic review is to determine optimal doses, routes of administration, and dosing strategies of naloxone for suspected opioid overdose in out-of-hospital settings, and whether transport to a hospital following successful opioid overdose reversal with naloxone is necessary.