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SAMHSA is committed to improving prevention, treatment, and recovery support services for mental and substance use disorders.
The Evidence-Based Practices Resource Center provides communities, clinicians, policy-makers and others with the information and tools to incorporate evidence-based practices into their communities or clinical settings.
The purpose of this systematic review is to determine optimal doses, routes of administration, and dosing strategies of naloxone for suspected opioid overdose in out-of-hospital settings, and whether transport to a hospital following successful opioid overdose reversal with naloxone is necessary.
Developed by AHRQ, this report reviews the scientific and grey literature about implementing medication-assisted treatment (MAT) for opioid use disorder (OUD) in rural primary care settings.
Systematic evidence review examining comparative effectiveness and harms of psychotherapy and medications for childhood anxiety disorders panic disorder, social anxiety disorder, specific phobias, generalized anxiety disorder, and separation anxiety.
Systematic evidence review assessing the effectiveness and harms of first- and second-generation antipsychotics FGAs and SGAs used for treating children, adolescents, and young adults.
The objective of this abstract is to assess the effectiveness of quality improvement, implementation, and dissemination strategies that seek to improve the mental health care of children and adolescents; to examine harms associated with these strategies; and to determine whether effectiveness or harms vary in subgroups based on system, organizational, practitioner, or patient characteristics.
This Technical Brief describes promising and innovative medication-assisted treatment (MAT) models of care in primary care settings, describe barriers to MAT implementation, summarize the evidence available on MAT models of care in primary care settings, identifies gaps in the evidence base, and guides future research.
Systematic evidence review comparing the effectiveness of strategies to prevent and de-escalate aggressive behaviors in psychiatric patients in acute care settings, including interventions aimed specifically at reducing use of seclusion and restraint.
Systematic evidence review describing and reviewing the effectiveness of interventions that address disparities among adult patients with serious mental illness.
This is a summary of a systematic review evaluating the evidence regarding the efficacy, comparative effectiveness, and adverse effects of medications in adults with Alcohol Use Disorder.
The AHRQ academy, which is a national resource for integrating behavioral health and primary care, offers guidance on how to integrate behavioral health and medication-assisted treatment for opioid use disorder into primary care or other ambulatory care settings to improve healthcare delivery and to achieve better patient outcomes.
The objective of this review is to compare the benefits and harms of second-generation antidepressants (SGAs), psychological, complementary and alternative medicine, and exercise treatment options as first-step interventions for adult outpatients with acute-phase major depressive disorder (MDD), and as second-step interventions for patients with MDD who did not achieve remission after a first treatment attempt with SGAs.
With this Guide, the National Institute on Alcohol Abuse and Alcoholism introduces a simple, quick, empirically derived tool for identifying youth at risk for alcohol-related problems.
Technical brief describes and compares four core management strategies to reduce psychiatric readmissions—length of stay for inpatient care, transition support services, short-term alternatives to psychiatric rehospitalization, and long-term approaches for reducing psychiatric rehospitalization—for patients at high risk of psychiatric readmission.
Systematic evidence review and meta-analysis of the efficacy, comparative effectiveness, and harms of medications both FDA approved and others for adults with alcohol-use disorders, and to evaluate the evidence from primary care settings.